AMPA Receptor Kinetic Simulator

Step 1: Transition-Rate Parameters

M⁻¹·s⁻¹ s⁻¹ M⁻¹·s⁻¹ s⁻¹ M⁻¹·s⁻¹ s⁻¹ M⁻¹·s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ M⁻¹·s⁻¹ s⁻¹ M⁻¹·s⁻¹ s⁻¹ M⁻¹·s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹ s⁻¹

Simulation Type:

Time Step (∆t) — simulation resolution:

Single-channel Conductance — O2 state (2 subunits open):

Single-channel Conductance — O3 state (3 subunits open):

Single-channel Conductance — O4 state (4 subunits open):

Pulse Duration (how long agonist is applied per concentration):

Maximum Simulation Time:

Agonist Pulse Start Time:

Agonist Pulse End Time:

Concentrations to Sweep(µM):